Abacavir sulfate is a synthetic carboxylic nucleoside drug, reverse transcriptase inhibitor, which is used to treat HIV and AIDS.
This drug has been associated with the occurrence of fatal hypersensitivity reaction. Symptoms include fever, skin rash, fatigue, gastrointestinal symptoms such as nausea, vomiting, diarrhea or abdominal pain. Others are respiratory symptoms such as pharyngitis, dyspnea or cough. Hypersensitivity is associated with the HLA-B*5701, for which before starting treatment with this drug it is necessary to conduct a study of the presence of this allele in the patient to avoid such a hypersensitivity reaction.
GENVINSET® HLA B57 is a kit for detecting HLA-B*57:01 alleles by Real Time PCR using TaqMan® probes technology.