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Genvinset®

Genvinset® HLA B57v5

Kit for detecting the HLA-B*57:01 alleles by Real-Time PCR using TaqMan® probes technology

Information about the product

The HLA-B*57:01 allele is a polymorphism of the HLA-B gene, which belongs to the MHC (Major Histocompatibility Complex) class I. This allele shows a frequency of around 3% in the European population.

 

INTENDED USE

Genvinset® HLA B57v5 is a semi-automated kit for the qualitative detection of the HLA-B*57:01 allele in genomic DNA extracted from whole blood, by Real-Time PCR using Taqman® probes technology.

The intended user of the kit is technical personnel trained to carry out the protocol and the interpretation of results described in this document.

 

WORKFLOW

 

RESULTS 

 

Limitations

  • See detected alleles acceding to Download section.
  • Mutations or polymorphisms at annealing primer/probe sites are possible and may result in the lack of allele definition. Other technologies could be necessary to resolve the typing.
  • Data and result interpretation should be revised by qualified personnel.

Downloads

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